The word reply is written in black and white on a white background.

Infertility Program

We help couples have a baby, without IVF

Transforming fertility care

At Reply, we don't accept "unexplained infertility” and we don't jump to IVF. Our medical solution recognizes that typically multiple factors contribute to fertility struggles. When these factors are identified and treated, you maximize your possibility for natural conception and a healthy pregnancy.

Infertility Q & A

RRM clinician and researcher Dr. Joseph Stanford reflects on the problem of infertility and the restorative solution.

  • The problem of infertility
  • How does RRM help?
  • Why isn't restoring health the norm?
  • How do patients respond to RRM?
  • What are outcomes with RRM?
  • Message for couples facing infertility
Joseph B. Stanford, MD, MSPH, CFCMC talking about infertility services.\

Our infertility program delivers

RRM by the numbers

50%

Pregnancy rate within 12 months at

< 1/2 cost of IVF

69%

Pregnancy rate within 18 months at

< 1/3 cost of IVF

71%

Reduction in preterm birth versus IVF

[5.7% RRM v. 10% US average v. 19% IVF]

50%

pregnancy @ 12 mos

< 1/2 cost of IVF

69%

pregnancy @ 18 mos

< 1/3 cost of IVF

71%

Reduction in preterm birth versus IVF

[5.7% RRM v. 10% US average v. 19% IVF]

Step into the future with restorative reproductive medicine

A man is hugging a pregnant woman in front of a window

  • Restorative

    Our aim with RRM is to cooperate with, restore, and support natural reproductive function. We recognize infertility is a symptom or sign of underlying conditions that needs to be identified and addressed. With this approach, the focus is not to “make a baby,” but to optimize your health so you can conceive on your own and grow your family with a foundation of good health.

  • Healthy

    Our focus with RRM is to optimize the health of mother, father, and offspring. RRM reduces risks inherent to IVF for mothers—such as hypertension, hemorrhage, and ovarian hyperstimulation syndrome—and for babies.Most significantly, the risk of preterm birth with RRM is only 5.7% compared to the 10.4% national and the 19.7% IVF average.

  • Effective

    Reply Fertility outcomes data show 50% of enrolled couples become pregnant within 12 months, and 69% become pregnant within 18 months. These data are consistent with RRM outcomes data published in the peer-reviewed medical literature, and are comparable to IVF outcomes that average 31% at cycle 1, 47% at cycle 2, and 71% at cycle 3.

  • Affordable

    Your financial health matters. RRM care fits into most household budgets, averaging 1/3 to 1/2 the cost of IVF. We are HSA/FSA eligible and offer flexible financing through CareCredit. Explore plans with the CareCredit calculator and see if you prequalify with no impact to your credit score.

  • Universal

    While assisted reproductive technology such as IVF poses health or ethical concerns for some couples, RRM care is universally acceptable to patients who may be motivated by personal philosophy or religious/cultural convictions to prefer holistic, natural solutions.

We've helped many couples who...

  • previously have failed with IVF or IUI
  • have suffered multiple miscarriages 
  • have been told they waited until they were “too old”
  • have been told they have low ovarian reserve
  • have been diagnosed as high-risk or unable to conceive
  • have been diagnosed with "unexplained infertility"
  • have suffered for years from PCOS or endometriosis with no diagnosis or ineffective treatment
  • have been told that male factor sperm quality requires IVF
  • are seeking more affordable treatment for infertility
  • are motivated by personal philosophy or religious conviction to seek natural/holistic solutions

Is RRM a fit for you?

Our program is for couples aiming to conceive naturally. 

 

  • female patients need to have at least one viable fallopian tube and cannot be in menopause
  • male patients may have suboptimal sperm, but would not be a fit if they have untreatable azoospermia 


Patients who previously have been sterilized would first need their procedure surgically reversed.

“ART [assisted reproductive technology such as IVF] increases the risk of preterm birth, low birth weight, and birth defects. These risks are particularly observed in multiple births; however, a certain risk increase remains also in singletons born after ART….In light of the safety of future ART generations, one rule should apply to all ART: if a method is clinically unnecessary, then avoid it.”

-- Pinborg A., Wennerholm U-B., Bergh C. Long-term outcomes for children conceived by assisted reproductive technology. Fertility and Sterility; September 2023; Vol 120, No. 3, Pt.1, p 453-454.

“ART offspring have an increased risk of NCD (noncommunicable diseases), such as malignancies, asthma, obesity, metabolic syndrome, diabetes, cardiovascular diseases, and neurodevelopmental and psychiatric disorders. There are still many controversies in this field and much remains unknown.”

-- Zhang S., Luo Q., Meng R., Yan J., Wu Y., Huang H.; Long-term health risk of offspring born from assisted reproductive technologies; Journal of Assisted Reproduction and Genetics; November 2023.

“There are substantial concerns about expanding use of IVF, including high cost and impact on neonatal outcomes. Epidemiologic studies have demonstrated higher incidence of preterm birth (PTB), low birthweight (LBW), and birth defects among children conceived through IVF….Our findings support efforts to encourage women to give an adequate trial of the least invasive fertility treatment that may work for them.”

-- Sanders, Jessia N, Simonsen Sara E., Porucznik Christina A., Hammoud Ahmad O., Smith Ken R., Stanford, Joseph B; Fertility treatments and the risk of preterm birth among women with subfertility: a linked-data retrospective cohort study; BMC Reproductive Health; March 2022

Expert findings about IVF concerns and risks

The growing body of evidence for RRM

Restorative reproductive medicine (RRM) is supported by peer-reviewed medical research and through the work of the International Institute for Restorative Reproductive Medicine (IIRRM). Reply Fertility collaborates with the IIRRM including as an enrolled clinic in the international research registry: Surveillance of Treatment Outcomes for Restorative Reproductive Medicine (STORRM).

Keep your family financially healthy, too

Our clinic provides similar efficacy to IVF at 1/3 to 1/2 the cost.

Reply Patient Journeys

A woman with long hair is wearing a turtleneck sweater and talking.

“Pregnancy felt impossible before we found Reply."

A woman wearing hoop earrings and a plaid shirt says reply fertility

“It felt custom-built, custom-fit just for me.”

A woman in a leopard print shirt is sitting in a chair

“Reply started my path to motherhood—a path no other doctor had given me.”

To hear more about the fertility journeys of Liz, Pam and Felishia, visit our video library.

What our patients are saying

"They have found things that the traditional fertility doctors overlooked…it’s so worth it to heal your bodies and prepare for a healthy pregnancy. I am truly so grateful this clinic exists!"

- Victoria S.

"Finding Reply gave me hope I hadn’t felt before. They slowed down the process, digging deeper to find out what was really wrong, then they treated the issues--monitoring every step--to ensure our success. We are now blessed with our beautiful daughter and hopeful to continue adding to our family!"

-Tracey L.

“Entire practice clearly values quality….Bravo, your commitment to patient care is quite evident!"

- B. L.

“Working with a practitioner in restorative reproductive medicine was one of the single best things we’ve ever done for our health. Reply changed my life forever.”

-anon

“We’d heard these horrible words, ‘unexplained infertility,’ which we thought just meant, ‘we'll never understand, we'll never know, it's hopeless.’ Before coming to you, we did not really know that there was much hope beyond being forced into IVF."

-anon

"Innovative. I have never been or heard of a practice that cares to work with both husband and wife to help them in various aspects of their 'reproductive' part of life, especially by helping them understand how it all works AND how to work with it to achieve desired outcomes.”

-anon

“It was such a deviation from what all these other doctors had done and what they had said and how they had treated me. It was the first that I felt like we were going to work together to figure it out.”

-Felishia W.B.

"My wife and I came to Reply to learn about fertility methods based on sound science and to learn more about fertility as a whole. We had a wonderful and empowering experience. We recommend Reply to anyone seeking to learn how to either avoid or accomplish getting pregnant as healthily as they can."

--Eddie D.

"I had very low expectations coming to this appointment. I really didn't expect her to be able to offer much as far as options go, however that was not the case. I felt so much hope leaving the appointment. Additionally, I felt my personal views opposing certain treatments were respected. I appreciated not having to explain myself."

-anon

"All the clinicians and staff at Reply are professional and caring. “

– S.G

"I cannot express enough gratitude for the compassionate care we received. Finding Reply—a doctor who truly cares about their patients—made the difference. They have so much knowledge and will use a variety of tools to help patients achieve a healthy pregnancy."

-Rachel B.

"Reply has amazing doctors whose aim is to care for the patient as a whole. Very compassionate and truly care for the patient…I highly recommend this practice!!!”

– Mary F.

“From the point that we felt we had the PCOS and everything else that it was causing under control…I think that was three months, and I was pregnant.”

-Pamela B.

“Reply is different. I think the focus being uncovering the underlying issue, it made Reply different than anywhere else. So that for us was the gamechanger.”

-Liz M.

“Being able to see my charts and compare test results with what my charts were showing was new to me. I had never had anyone do that before…I wish I had been educated like this a long time ago.”

--Rachel R.

"Reply is a fantastic resource for women’s needs. They were very knowledgeable….The doctors and nurses care and they are connected to other specialists so that you get the answers you need. I would not hesitate to recommend Reply."

– Laura F.

"The staff was very kind, helpful and thoughtful regarding my fertility issues. They also helped my husband and provided resources for him."

--Crystal B.
Share by: